Hydroquinone 12% cream

Skincare

Hydroquinone

Advanced Skin Brightening Formula for Stubborn Hyperpigmentation

Hydroquinone 12% Cream is a high-strength, prescription-grade topical treatment used to visibly reduce the appearance of melasma, age spots, sun damage, and post-inflammatory hyperpigmentation (PIH). This formulation is intended for short-term use under medical supervision and is ideal for patients who have not responded to lower-concentration products.

Understanding Hydroquinone

Hydroquinone is a melanin synthesis inhibitor that works by blocking the enzyme tyrosinase, which is necessary for the production of melanin (pigment). By decreasing melanin production, it helps to fade dark patches and even out skin tone.

This 12% concentration is significantly stronger than over-the-counter formulations (typically 2%) and is recommended for patients with persistent or treatment-resistant discoloration. It should be used with caution and as part of a complete skin care plan monitored by a medical provider.

Potential Benefits
  • Fades Dark Spots: Targets areas of hyperpigmentation caused by sun exposure, aging, or inflammation.
  • Improves Skin Tone Uniformity: Helps restore a more even, radiant complexion.
  • Targets Melasma & PIH: Especially effective on hormonal pigmentation and post-acne discoloration.
  • Prescription Strength: Higher concentration designed for patients with minimal response to OTC treatments.
  • Fast-Acting Results: Visible improvement may be seen in as little as 4–8 weeks with consistent use.
Key Ingredients
  • Hydroquinone 12%:
    A powerful skin-lightening agent that reduces melanin production at the cellular level.

  • Base Cream Components (may include):
    Emollients, water, glycerin, and stabilizers to ensure proper absorption and skin tolerance. Exact formulation may vary by compounding pharmacy.

This formulation is typically compounded and may include additional ingredients tailored to your skin’s needs (e.g., tretinoin or hydrocortisone if prescribed).

Warnings & Important Information
  • For External Use Only:
    Avoid contact with eyes, mucous membranes, or broken skin.
  • Short-Term Use Only:
    Due to potential skin sensitivity or ochronosis (bluish-black discoloration), Hydroquinone 12% should not be used for longer than 12 weeks unless directed by a provider.
  • Sun Protection Required:
    This product increases sun sensitivity. Daily use of broad-spectrum SPF 30+ is essential to prevent further pigmentation.
  • Not for All Skin Types:
    Individuals with very sensitive skin or darker Fitzpatrick skin types should use with caution to avoid hypopigmentation or irritation.
  • Pregnancy Warning:
    Not recommended for use during pregnancy or breastfeeding.
  • Side Effects May Include:
    Mild irritation, redness, dryness, or stinging. Discontinue use and consult your provider if severe irritation or allergic reaction occurs.
  • Requires Prescription:
    Hydroquinone 12% is a high-potency compound that must be used under the guidance of a licensed provider.