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*Image for illustration only. Medication is compounded and dispensed by a licensed third-party pharmacy.

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GLP-1²

A Dual-Action Breakthrough in Weight Management & Metabolic Health

GLP-1² is a formulation that synergistically combines semaglutide and tirzepatide—two advanced GLP-1 receptor agonists—in one compounded treatment. 

If right for you, your DrWell Provider may prescribe GLP-1² in an dose they deem necessary and appropriate based on your individual medical needs.

Understanding GLP-1²

GLP-1² brings together two active ingredients that work on complementary pathways:

  • Semaglutide is a GLP-1 receptor agonist.

  • Tirzepatide is a dual GIP/GLP-1 receptor agonist.

Combining these two, GLP-1² offers a dual-action approach.

Why Combine Semaglutide + Tirzepatide?
Dr. Kaplan, founder of DrWell noticed in his patients will less appetite suppression who switched from semaglutide to tirzepatide, had improved appetite suppression but their food noise returned. His nurse practitioner suggested treating patients with a combined off-label regimen to help their patients with both food noise reduction and appetite suppression.
Warnings & Considerations:

GLP-1² is a prescription-only compounded medication formulation. If prescribed for you, it is administered under the supervision of a licensed DrWell Provider. As with all GLP-1 therapies, there are important safety considerations:

  • Not suitable for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

  • May cause nausea, vomiting, diarrhea, especially during dose titration

  • Monitor for signs of pancreatitis, gallbladder issues, or allergic reactions

  • Not indicated for patients with Type 1 diabetes or those with severe gastrointestinal disorders

Regular follow-ups, lab monitoring, and dose adjustments are part of the DrWell Methodology to ensure safe, effective outcomes.

Available from DrWell Providers

The GLP-1² formulation is not available in most pharmacies or over-the-counter. This unique formulation is custom compounded pursuant to a patient-specific prescription and dispensed to patients enrolled in a medically supervised program through DrWell Providers. This ensures the highest standard of care, safety, and results-driven outcomes.

*Available by prescription only if medically necessary for your specific medical need as determined by your provider. Compounded medications have not been evaluated by the FDA for safety, quality, or efficacy.  They are indicated for patients when a prescribing practitioner determines that the compounded preparation produces a significant difference for their patient compared to an FDA-approved product. If prescribed by your DrWell provider, your prescription will be dispensed from a state-licensed third-party compounding pharmacy. 

The content on this website is for informational purposes only and is not a substitute for professional medical advice.