Compounded Semaglutide
A once-weekly injectable used in medically supervised weight management programs, prescribed and monitored by a licensed provider.
Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.
See it before your first visit
Photographs of the medication as dispensed.
What it is
Semaglutide belongs to a class of medications called GLP-1 receptor agonists. It is prescribed as part of a supervised weight management program alongside changes to nutrition and activity, not as a standalone treatment.
The compounded form is prepared by a licensed pharmacy for an individual patient based on a prescription. It is not the same as a commercially manufactured product, and it is not reviewed or approved by the FDA.
How it works
GLP-1 is a hormone the body releases after eating. It signals fullness to the brain, slows how quickly the stomach empties, and supports the pancreas in releasing insulin when blood sugar rises.
Semaglutide mimics that signal and stays active far longer than the natural hormone, which is why it is dosed weekly rather than daily.
What to expect
Treatment usually begins at a low dose and increases in steps over several weeks. This titration is deliberate: it gives the digestive system time to adjust and is the main lever your provider uses to manage side effects.
Your provider decides when to advance a dose, hold it, or step it back. Individual responses vary, and no specific outcome is promised or implied.
Who it is for
Candidacy is determined by a licensed provider after reviewing your medical history, current medications and goals. Programs are generally intended for adults being treated for weight management under ongoing clinical supervision.
This page is general information. It is not medical advice and it is not a substitute for a consultation.
Side effects
The most commonly reported side effects are gastrointestinal: nausea, vomiting, diarrhea, constipation and abdominal pain. These are often most noticeable after a dose increase.
Less common but serious reported effects include pancreatitis, gallbladder disease, kidney injury related to dehydration, and allergic reactions. Contact your provider promptly about severe or persistent abdominal pain.
Read this before you start
Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.
Medication availability, formulation, packaging and pharmacy fulfillment vary based on the patient's prescription and location.
Boxed warning. In rodent studies, semaglutide caused thyroid C-cell tumors. Whether it causes these tumors in humans, including medullary thyroid carcinoma, has not been determined. It should not be used by anyone with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.
Compounding status. Compounded medications are prepared by a licensed pharmacy for an individual patient. They are not FDA approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.
Not medical advice. The information on this page is general and educational. It does not establish a provider relationship, does not replace a consultation, and should not be used to self-diagnose or self-treat. Talk to a licensed provider about whether any medication is appropriate for you.
No guaranteed outcome. Individual results vary. Nothing on this page should be read as a promise of a specific result.
Common questions
Is compounded semaglutide the same as the brand-name product?
No. A compounded preparation is made by a licensed pharmacy for an individual patient. It is not an FDA-approved product and is not evaluated by the FDA before it is dispensed.
How is it prescribed?
Only by a licensed provider, after a clinical evaluation. Providers in the DrWell network review your history and decide whether a program is appropriate.
Where is it made?
Every pharmacy in the DrWell network clears a published vetting standard before an order can route to it, covering licensure, accreditation, cGMP for 503B facilities, third-party potency and sterility testing, and recall history.
What if I have side effects?
Contact your prescribing provider. Do not adjust your own dose. Seek urgent care for severe abdominal pain, signs of an allergic reaction, or symptoms that worsen quickly.
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