NAD+ Nasal Spray
A compounded NAD+ nasal spray that a licensed provider may prescribe as part of a longevity and wellness program, based on clinical evaluation. Compounded medications are not FDA approved.
Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.
See it before your first visit
Photographs of the medication as dispensed.
What it is
NAD+ (nicotinamide adenine dinucleotide) is a molecule found in every cell of the body. It is involved in how cells make energy and carry out routine repair. A licensed provider may prescribe a nasal spray form as part of a longevity and wellness program after reviewing your health history, medications and goals.
Research on NAD+ levels and aging is active, but large, well-controlled human trials of NAD+ nasal sprays for wellness or longevity are limited.
This medication is compounded. It is prepared by a licensed pharmacy for an individual patient based on a prescription. Compounded medications are not FDA approved, which means the FDA has not evaluated their safety, effectiveness or quality.
How it works
Cells use NAD+ to convert nutrients into energy and to support enzymes involved in DNA repair and other cell processes. NAD+ levels in the body decline with age, and researchers are studying whether replenishing it has health effects.
A nasal spray delivers the medication through the lining of the nose. It has not been established how much NAD+ is absorbed this way or whether it improves health outcomes. Your provider determines whether NAD+ is appropriate for you and sets the dose.
What to expect
Your provider will review your health history and current medications before prescribing, and will explain the dose and how to use the spray correctly. Follow-up visits are part of treatment.
Some people notice nasal irritation or a mild stinging after a dose. Because human evidence is limited, no specific outcome can be promised. Individual responses vary, and results are not guaranteed.
Who it is for
Whether NAD+ nasal spray is appropriate for you is a decision made by a licensed provider based on your health history, medications and goals. It is not appropriate for everyone, including people who are pregnant or nursing.
This page is general information and is not medical advice.
Side effects
Commonly reported side effects include nasal irritation, stinging, dryness, runny nose, sneezing, nosebleeds, headache, nausea and flushing.
Allergic reactions are possible. Contact your provider promptly about chest pain, trouble breathing, swelling of the face or throat, a spreading rash, fainting, or nosebleeds that do not stop.
This is not a complete list. Ask your provider about the full prescribing information.
Read this before you start
Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.
Medication availability, formulation, packaging and pharmacy fulfillment vary based on the patient's prescription and location.
Compounded medication. This medication is compounded by a licensed pharmacy and is not FDA approved. The FDA has not evaluated compounded medications for safety, effectiveness or quality. It is prescribed for an individual patient by a licensed provider.
Limited human evidence. NAD+ nasal sprays have not been shown in large, well-controlled clinical trials to be safe or effective for wellness or longevity uses. Long-term safety is unknown.
Nasal health. Tell your provider if you have chronic nasal or sinus problems, frequent nosebleeds, or have had nasal surgery.
Cancer history. Tell your provider if you have a history of cancer or a condition that involves abnormal cell growth. The effect of raising NAD+ levels in these settings is not known.
Pregnancy and nursing. Do not use if you are pregnant, planning to become pregnant or nursing unless your provider directs otherwise.
Use and sharing. Use only as directed by your provider. Do not share the spray with anyone else.
Not medical advice. The information on this page is general and educational. It does not establish a provider relationship and does not replace a consultation with a licensed provider.
Common questions
Is NAD+ nasal spray FDA approved?
No. This medication is compounded by a licensed pharmacy, and compounded medications are not FDA approved. The FDA has not evaluated them for safety, effectiveness or quality.
How is it different from the injection?
The spray is absorbed through the lining of the nose, while the injection goes under the skin. It is not established how the two compare. Your provider can explain which form may fit your situation.
Does it slow aging?
That has not been shown. Research is active, but large, well-controlled human trials of NAD+ nasal sprays are limited. No specific outcome can be promised.
How do I use it?
Exactly as your provider directs. Do not change the dose or schedule on your own.
What if I have side effects?
Contact your prescribing provider. Seek urgent care for trouble breathing or signs of a serious allergic reaction.
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