A compounded synthetic peptide that a licensed provider may prescribe after clinical evaluation. Human research data is limited. Compounded medications are not FDA approved.
Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.

Images are for illustrative purposes only. Actual medication appearance, packaging, and labeling may vary by pharmacy.



Semax is a synthetic peptide based on a fragment of adrenocorticotropic hormone (ACTH), a natural hormone. It was developed and studied mainly in Russia. People often ask about it in connection with cognitive support, blood flow in the brain and migraines. A licensed provider decides whether it is appropriate for you after reviewing your health history and medications.
Human research on Semax is limited, and much of it was done outside the United States. It has not been shown in large, well-controlled clinical trials in the United States to be safe or effective for any use. Semax is not FDA approved to prevent or treat migraine or any other condition.
This medication is compounded. It is prepared for an individual patient based on a prescription. DrWell sources compounded peptides from prevetted 503A compounding pharmacies. Compounded medications are not FDA approved, which means the FDA has not evaluated their safety, effectiveness or quality.
Laboratory and animal research has looked at whether Semax influences brain signaling molecules involved in learning and memory, and whether it affects blood flow in the brain.
These effects have not been established in humans. Your provider determines whether Semax is appropriate for you and how it should be used.
Your provider will review your health history and current medications before prescribing, and will explain the dose, schedule and how to use it. Follow-up visits are part of treatment.
Because human evidence is limited, no specific outcome can be promised. Individual responses vary, and results are not guaranteed.
Whether Semax is appropriate for you is a decision made by a licensed provider based on your health history, medications and goals. It is not appropriate for everyone, including people who are pregnant or nursing and people with a bleeding disorder or who take blood thinners, unless your provider directs otherwise.
This page is general information and is not medical advice.
Because human safety data are limited, the full range of side effects is not known. Reported or expected effects of peptide treatments in general include irritation, redness or discomfort where the medication is applied or injected, headache, dizziness, nausea and fatigue. Allergic reactions are possible. Because Semax may affect bleeding, bruising or unusual bleeding is possible.
Contact your provider promptly about unusual bleeding or bruising, swelling, trouble breathing, a spreading rash, or any symptom that concerns you.
This is not a complete list. Ask your provider for more information.
Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.
Medication availability, formulation, packaging and pharmacy fulfillment vary based on the patient's prescription and location.
Compounded medication, not FDA approved. This medication is compounded and is not FDA approved. The FDA has not evaluated compounded medications for safety, effectiveness or quality. It is prescribed for an individual patient by a licensed provider.
Pharmacy sourcing. DrWell obtains this medication from prevetted 503A compounding pharmacies. Sourcing from a vetted pharmacy does not make a compounded medication FDA approved and does not establish that it is safe or effective.
Limited human evidence. Semax has been studied mainly in laboratory and animal research and in limited human studies done largely outside the United States. It has not been shown in large, well-controlled clinical trials to be safe or effective in people. Long-term safety is unknown.
Bleeding risk. Semax may increase the risk of bleeding. Tell your provider if you have a bleeding disorder, take blood thinners or antiplatelet medication, or have surgery planned.
Pregnancy and nursing. Do not use if you are pregnant, planning to become pregnant or nursing unless your provider directs otherwise.
Monitoring. Your provider should monitor your health during treatment.
Not medical advice. The information on this page is general and educational. It does not establish a provider relationship and does not replace a consultation with a licensed provider.
No. Semax is compounded, and compounded medications are not FDA approved. The FDA has not evaluated them for safety, effectiveness or quality.
A synthetic peptide based on a fragment of adrenocorticotropic hormone (ACTH). It was developed and studied mainly in Russia.
Limited, and much of it was done outside the United States. It has not been shown in large, well-controlled clinical trials to be safe or effective in people.
From prevetted 503A compounding pharmacies. That does not make it FDA approved, and it does not establish that it is safe or effective.
That has not been shown in people. Semax is not FDA approved to prevent or treat migraine or any other condition. No specific outcome can be promised.
It may. Tell your provider if you have a bleeding disorder, take blood thinners or antiplatelet medication, or have surgery planned.
Exactly as your provider directs. Do not change the dose or schedule on your own.
Contact your prescribing provider. Seek urgent care for unusual bleeding, swelling, trouble breathing or signs of a serious allergic reaction.