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Men's Health
Compounded, not FDA approved

Sildenafil

Compounded sildenafil, a PDE5 inhibitor

Compounded sildenafil, an oral PDE5 inhibitor that a licensed DrWell provider may prescribe for erectile dysfunction as part of a sexual wellness program, based on clinical evaluation and health history. Compounded medications are not FDA approved.

Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.

Prescription medication. Medication availability, formulation, packaging and pharmacy fulfillment vary based on the patient's prescription and location.
Sildenafil
At a glance
Dosing and schedule are set by your provider
Form and route
Oral, as directed by your prescriber
Frequency
As needed, as directed by your prescriber
Storage
As directed on your pharmacy label
Category
Men's Health
Gallery

See it before your first visit

Photographs of the medication as dispensed.

Overview

What it is

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor. A licensed DrWell provider may prescribe it for erectile dysfunction (ED) as part of a sexual wellness program after reviewing your symptoms, medications and health history.

The brand-name version of sildenafil, Viagra, is FDA approved. The sildenafil offered here is compounded. It is prepared by a licensed pharmacy for an individual patient based on a prescription. Compounded medications are not FDA approved, which means the FDA has not evaluated their safety, effectiveness or quality.

Mechanism

How it works

Sildenafil blocks an enzyme called PDE5. Blocking it helps blood vessels relax and widen, which increases blood flow. It works in response to sexual stimulation and does not cause arousal on its own.

Your provider determines the dose and how it should be used, and may adjust it based on how you respond.

The program

What to expect

Your provider will review your health history, blood pressure and every medication you take before prescribing. Your provider will tell you how much to use and when, and may change the plan over time.

Individual responses vary, and results are not guaranteed.

Candidacy

Who it is for

Whether sildenafil is appropriate for you is a decision made by a licensed provider based on your symptoms, examination and health history. It is not appropriate for everyone, including people who take nitrate medications and people with certain heart conditions.

Sexual health concerns can have many causes, including heart health, diabetes, hormone levels and medications. Your provider will evaluate the full picture.

This page is general information and is not medical advice.

Tolerability

Side effects

Commonly reported side effects include headache, flushing, nasal congestion, upset stomach, dizziness and changes in vision such as a blue tint or sensitivity to light.

Serious risks include a drop in blood pressure, especially when combined with nitrates or certain other medications; an erection that lasts more than four hours (priapism); sudden vision loss in one or both eyes; and sudden decrease or loss of hearing. Seek urgent care for chest pain, fainting, an erection lasting more than four hours, or any sudden change in vision or hearing.

This is not a complete list. Ask your provider about the full prescribing information.

Safety information and disclosures

Read this before you start

Compounded, not FDA approved
Prescription only
Provider supervision required

Compounded drugs are not FDA approved. FDA does not review compounded drugs for safety, effectiveness, or quality before marketing.

Medication availability, formulation, packaging and pharmacy fulfillment vary based on the patient's prescription and location.

Compounded medication. This medication is compounded by a licensed pharmacy and is not FDA approved. The FDA has not evaluated compounded medications for safety, effectiveness or quality. It is prescribed for an individual patient by a licensed provider.

Nitrates. Never take sildenafil if you use nitrate medications, including nitroglycerin, or recreational nitrites known as poppers. The combination can cause a sudden, dangerous drop in blood pressure.

Other medications. Tell your provider about all medications you take, especially alpha blockers, blood pressure medications, riociguat and certain antifungals and antivirals.

Heart health. Sexual activity carries some cardiac risk. Tell your provider if you have heart disease, low or uncontrolled high blood pressure, a history of stroke, or liver or kidney disease.

Vision and hearing. Stop use and get medical help right away if you notice sudden vision or hearing loss.

Not medical advice. The information on this page is general and educational. It does not establish a provider relationship and does not replace a consultation with a licensed provider.

If you are having a medical emergency, call 911. The information on this page is general and educational. It does not establish a provider relationship, does not replace a consultation, and should not be used to diagnose or treat any condition.
Questions

Common questions

What is sildenafil?

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor. A licensed provider may prescribe it for erectile dysfunction (ED). The version offered here is compounded.

What is sildenafil used for?

Sildenafil is prescribed for erectile dysfunction, which is difficulty getting or keeping an erection firm enough for sex. Your provider evaluates the cause, which can include heart health, diabetes, hormone levels and medications.

Is compounded sildenafil FDA approved?

No. It is compounded by a licensed pharmacy, and compounded medications are not FDA approved. The FDA has not evaluated them for safety, effectiveness or quality. The brand-name version, Viagra, is FDA approved.

How does sildenafil work?

Sildenafil blocks an enzyme called PDE5, which helps blood vessels relax and widen and increases blood flow. It works in response to sexual stimulation and does not cause arousal on its own.

How long does sildenafil last?

Its effects last for several hours, and how long varies by person. Your provider will explain when and how to use it. Do not take more than prescribed.

What is the difference between sildenafil and tadalafil?

Both are PDE5 inhibitors prescribed for erectile dysfunction. They differ in how quickly they work and how long their effects last. DrWell also offers compounded tadalafil, and your provider can help decide which fits you.

Can I take sildenafil with nitrates?

No. Taking sildenafil with nitrate medications, including nitroglycerin and recreational nitrites known as poppers, can cause a sudden, dangerous drop in blood pressure. Tell your provider about every medication you take.

What are the side effects of sildenafil?

Commonly reported side effects include headache, flushing, nasal congestion, upset stomach, dizziness and changes in vision such as a blue tint or sensitivity to light. Serious risks include a sudden drop in blood pressure, an erection lasting more than four hours, and sudden vision or hearing loss. See the side effects section above and ask your provider about the full prescribing information.

Does sildenafil lower blood pressure?

It can cause a small drop in blood pressure, and the drop can be dangerous if you also take nitrates or certain other medications. Tell your provider about your blood pressure and every medication you take.

Does it cause arousal on its own?

No. It works in response to sexual stimulation.

How do I take it?

Exactly as your provider directs. Do not take more than prescribed or change your dose on your own.

Can I get a sildenafil prescription from DrWell?

Prescriptions can be written by a licensed DrWell provider after an evaluation of your symptoms, medications and health history. Whether treatment is appropriate is the provider's decision.

How much does sildenafil cost?

Costs vary. They depend on your prescribed dose and your pharmacy. Your DrWell provider can explain what applies to you.

What if I have side effects?

Contact your prescribing provider. Seek urgent care for chest pain, fainting, an erection lasting more than four hours, or sudden vision or hearing changes.